Since the beginning of 2011, more than 500 homes, wells and other structures have been destroyed in the West Bank and East Jerusalem, displacing over 1,000 Palestinians, UN figures show.
This is twice as many people over the same time period last year and the highest figure since 2005. Half of those displaced are children.
Around 4,000 housing units have been approved in East Jerusalem over the past year, the highest number since 2006, the Israeli organization Peace Now said.
Settler attacks against Palestinians have increased by over 50 percent in 2011 compared to 2010, and by 160 percent since 2009, UN reports show.
Meanwhile, over 10,000 olive and other trees have been destroyed this year.
"The Quartet should call ongoing settlement expansion and house demolitions what they are: violations of international humanitarian law that Israel should stop," said Sarah Leah Whitson, Middle East director at Human Rights Watch.
Phillip Luther, regional director for Amnesty International, said the figures show the Quartet's approach has failed.
"Israel’s escalating violations show the fundamental failure of the Quartet’s approach. It’s time for the Quartet to understand that they cannot contribute to achieving a just and durable solution to the conflict without first ensuring respect for international law."